2026 Publications
The ENL-USP7 Complex Regulates HIV Latency Through BRD4 Stabilization
Characterization Standard for In-situ Cryo-electron Tomography
HIV-1 uncoating location dictates sites of integration
Temporal Evolution of Drug Resistance to HIV Integrase Inhibitors
The virus lesson: Teaching viral structure and quasi-symmetry in mixed reality
Mechanism of HIV-1 Capsid Rupture and Uncoating by Reverse Transcription
Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly
The host protein cyclophilin A restricts nuclear entry of HIV-1 mutants by reducing the elasticity of the viral capsid
Lenacapavir-induced lattice hyperstabilization is central to HIV-1 capsid failure at the nuclear pore complex and in the cytoplasm
Cryoelectron tomography of HIV-1 cell-cell transmission conjugates reveals a secluded environment for viral assembly and transfer
The central pore of HIV-1 capsomers promotes sustained stability of the viral capsid
Histone decrotonylation plays a distinct role in HIV latency
Real-Time Imaging of HIV-1 Protease Activation and Substrate Cleavage in Single Virions Assembling on the Plasma Membrane
Damaging the conical morphology of HIV-1 capsid by targeting the FG-binding pocket and disfavoring pentameric subunits needed for core closure
HIV-1 capsid interactions with Nuclear Pore Complex components support nuclear entry via affinity gradient
HIV expression persists in the cerebrospinal fluid of HIV-associated neurocognitive disorders despite effective ART
PMID: 41527791
PMCID: PMC12872101
Psi RNA-specific Binding Promotes HIV-1 Gag Conformational Change Critical for Immature Viral Particle Assembly
Lenacapavir prevents production of infectious HIV-1 by abrogating immature virus assembly
Mol*web molecular graphics engine
MolViewStories: Interactive molecular storytelling
Predicting water at the protein interface in cryo-EM structures from MD-excess chemical potential
Toward Reconciling the Standard Binding Free Energy of Lenacapavir to HIV-1 Capsid with Experiment: Thermodynamic Effects of Solvent Buffer and Ligand Reorganization
Human RPL7 and DDX21 function synergistically with HTLV-1 Gag to overcome genomic RNA structural barriers that block tRNA pro primer annealing
Super-Resolution Imaging of Nuclear Pore Responses to Mechanical Stress and Energy Depletion
Cryo-electron tomography of Nipah virus structural protein complexes in virus-like particles
Ordered release of genomic RNA during icosahedral virus disassembly
